
Disulfiram
Disulfiram (Antabuse) is a drug that is prescribed for treating chronic alcoholism. Well, Disulfiram never cures alcoholism, but it only adds to the supportive therapy.
Drug Class and Mechanism
Disulfiram works by blocking the oxidation of alcohol in the body. The drug is known to increase the acetaldehyde concentration in the blood. A person who has taken Disulfiram is likely to come across unpleasant reactions even if alcohol is taken in small quantities.
How to use
Disulfiram is an oral drug. The medicine has to be taken as per the prescription. The normal dosage is two or three tablets a day. The drug has to be swallowed and if there is any problem in doing so, it can be crushed or mixed with some liquid and taken.
Missed Dose
If an Disulfiram dose is missed, take the missed one as soon as you realise it. But care should be taken not to take the drug if it is almost time for the next scheduled dose. Never mix two doses of Disulfiram.
If you fee of having taken an over dose of the drug, contact your doctor immediately. Nausea, dizziness, vomiting, loss of coordination, seizures and tingling are some of the side effects that come with an Disulfiram overdose.
Warnings/precautions
It is always better to take Disulfiram after consulting the doctor. When talking with your doctor, tell him about all your preset and past health problems, which help him to make a right decision on the medication. Frankly tell him if you are having epilepsy, kidney or liver disease, thyroid problems, diabetes, mental disorders, brain damage or seizure disorders.
The drug is rated FDA pregnancy category C, which means that it is not known if the drug can cause harm to the unborn or the newborn babe. Even then, if pregnant or breast feeding, it is good to take the medicine only after consulting your doctor.
When you are taking Disulfiram, you should avoid all kinds of alcohols. You should also be aware of the products that contain alcohol. Keep away from products like mouthwash, aftershave lotions, colognes and other medicines, which all contain alcohol. After taking Disulfiram, you should no consume alcohol for the next 12 hours.
Side effects
Just like all drugs, Disulfiram also comes with many side effects. While taking the drug, some people may come across allergic reactions like swelling (lips, face, tongue) and hives.
Shortness of breath, seizures, tiredness, yellowing of skin or eyes, dark urine, appetite changes, dizziness, vomiting, weakness and severe diarrhoea are some of the severe side effects that come with Disulfiram. If you come across any of these conditions, better stop the drug and contact your doctor immediately.
Some of the lesser-known side effects that one experience with Disulfiram are skin rashes, mild headaches, metallic taste, mild weakness and dizziness, and swollen tongue.
Storage
Disulfiram has to be stored at room temperatures between 59 degrees F and 86 degrees F. The drug has to be stored in tight containers and kept away from light and heat.